Developmental BiologyDevelopmentPeer-reviewed
Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo.
Swann Floc’hlay, Maria Dolores Molina, Céline Hernandez…·Denis Thieffry
The paper develops a computational model of the Nodal and BMP2/4 signaling pathways in sea urchin embryos, showing BMP dominance and the importance of Smad activation rates in dorsal-ventral patterning.