Author
National University of SingaporeORCID 0000-0003-2929-8966Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Bo Burla, Guoshou Teo, Peter Imre Benke…·Hyungwon Choi
MRMhub automates processing of large-scale targeted metabolomics data, offering scalability and quality control tools, and is validated on lipidomics datasets.
Claire Bellis, Gabriel Kolle, Jacklyn Yong…·Patrick B. O. Tan
The paper describes the development of a national genomic infrastructure in Singapore to scale precision medicine, achieving high throughput and operational efficiency in genome sequencing.
Pritesh Jain, Hong Kiat Ng, Darwin Tay…·John Campbell Chambers
The paper identifies DNA methylation biomarkers predictive of Type-2 diabetes in Asian populations and shows their utility in risk stratification.
Mélanie Guirette, Jessie Jie Lan, Nicola Mary McKeown…·On behalf of the CHARGE Gene-Lifestyle Interactions Working Group
The paper identifies novel genetic loci associated with systolic blood pressure that interact with the DASH diet score through genome-wide interaction analysis.
Yu Xu, Scott C. Ritchie, Yujian Liang…·Michael Inouye
The paper develops genetic scores for 17,227 molecular traits using multi-omic data from INTERVAL and validates them across ancestries, demonstrating their utility in pathway analysis and disease association discovery.
Hwee Hui Lau, Nicole A. J. Krentz, Fernando Abaitua…·Adrian Kee Keong Teo
This study shows that PAX4 variants reduce beta cell function and increase diabetes risk by impairing insulin secretion and hormone gene expression in human cells.