Alfonso Urbanucci

This study shows that inhibiting PGM3 in pancreatic cancer cells disrupts DNA repair pathways, induces a BRCAness-like state, and increases sensitivity to PARP inhibitors and radiation.

The paper identifies a SOX4-driven regulatory program that promotes enzalutamide resistance in prostate cancer by rewiring gene regulation following AR suppression.

The paper identifies molecular signatures in prostate cancer that link inflammatory chemokine expression to metabolic changes and relapse risk.

The paper identifies club-like cells in the prostate tumor microenvironment that contribute to androgen deprivation therapy resistance through immune suppression.

The paper quantifies tumor-specific total mRNA expression from bulk data and shows its association with clinical outcomes across 15 cancer types.

This study investigates the role of the paternally expressed Snord116 gene in hypothalamic orexin neurons and its impact on sleep and metabolic functions in mice with paternal deletion of Snord116.