Hydrodynamic dispersion drives viral-cellular contact for gene delivery in porous media
Vishal Srikanth, Micah Mallory, Andrew J. Ulmer, Wesley R. Legant, Andrey V. Kuznetsov, Yevgeny Brudno
The paper shows that hydrodynamic dispersion in porous media enhances viral-cellular collisions, improving transduction efficiency by overcoming sedimentation-diffusion limitations.
Proceedings of the National Academy of Sciences · Jul 15, 2026Peer-reviewedBioengineering