Author

Tyler Harvey

Broad InstituteORCID 0000-0003-2972-8911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:machine learning (classical)· 2 Organism:mouse· 2

Frequent Co-Authors

Avinash WaghrayiD· 2 shared Ayshwarya SubramanianiD· 2 shared Christoph MuusiD· 2 shared Daniel T. MontoroiD· 2 shared Graham HeimbergiD· 2 shared Joshua GouldiD· 2 shared Karthik A. JagadeeshiD· 2 shared Michael Alexander Leney-GreeneiD· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Avinash WaghrayORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 10, 2023

Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene Scleraxis to Instruct Regeneration

Yun Bai, Tyler Harvey, Colin Bilyou…·Chen‐Ming Fan

This study shows that Scx is required for satellite cell expansion and muscle regeneration, with distinct target genes from tendon development.

5 citations

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 25, 2021

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

Toni Marie Delorey, Carly G.K. Ziegler, Graham Heimberg…·Alexandra–Chloé Villani

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

40 citations

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 19, 2020

✦ In-depth digest

Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells

Christoph Muus, Malte D. Luecken, Gökçen Eraslan…·Wenjun Yan

Across 1,176,683 airway and lung cells from 22 datasets, ACE2 rises with age, in males and in smokers' multiciliated cells, and is lowest in young children.

236 citations

𝕏 PostBluesky