Mari T. Kaartinen

Off-target genomic effects in MRP8-Cre driver mice complicate its use in weight gain and metabolic studies

This study shows that MRP8-Cre mice have off-target deletions affecting genes involved in thromboinflammation and metabolism, making them unsuitable for studying weight gain and metabolic disorders.

Circulating plasma fibronectin affects normal adipose tissue insulin sensitivity and adipocyte differentiation

This study shows that lack of plasma fibronectin improves insulin sensitivity and adipocyte differentiation in adipose tissue.