Vladimir Galatenko

Four-model hiPSC screen in 384-well imaging reached 83% accuracy (88% sensitivity, 75% specificity) on 130 scored compounds from a 146-compound reference set, scalable to hundreds of compounds monthly.

The paper identifies molecular asymmetries in the rat hypothalamus that support hemisphere-specific neuroendocrine signaling through gene expression and functional experiments.

evoGO minimizes redundancy in GO enrichment analysis by considering the GO hierarchy, improving specificity while preserving relevant biological information.

The paper investigates how left and right brain injuries affect the endocrine system differently, revealing a bipartite neuroendocrine system that mediates contralateral effects through distinct molecular and neural mechanisms.

This study shows that unilateral brain injury in rats causes motor asymmetry and gene expression changes in the spinal cord, mediated by neurohormonal signaling from the injured brain.