Pharmacology & ToxicologybioRxivPreprint
✦ In-depth digest
A human induced pluripotent stem cell-based high-throughput screening platform for teratogenicity hazard identification
Henrik Renner, Kinga Maria Wrona, Christopher Bruhn…·Bastian Zimmer
Four-model hiPSC screen in 384-well imaging reached 83% accuracy (88% sensitivity, 75% specificity) on 130 scored compounds from a 146-compound reference set, scalable to hundreds of compounds monthly.