Author

Guoyu Yu

The University of Texas MD Anderson Cancer CenterORCID 0000-0003-3030-5983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Celia Sze Ling Mak· 1 shared Christopher J. LogothetisiD· 1 shared Guocan WangiD· 1 shared Jian H. SongiD· 1 shared Jianhua Zhang· 1 shared Jingjing Liu· 1 shared Marites Pasuelo MelanconiD· 1 shared Miao ZhangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Celia Sze Ling Mak

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 5, 2024

Prostate cancer-induced endothelial-to-osteoblast transition generates an immunosuppressive bone tumor microenvironment

Guoyu Yu, Paul Gettys Corn, Celia Sze Ling Mak…·Sue-Hwa Lin

This study identifies a prostate cancer-induced endothelial-to-osteoblast transition that creates an immunosuppressive bone tumor microenvironment, reducing the effectiveness of immune checkpoint therapy in bone metastatic castrate-resistant prostate cancer.

51 citationstop 2%

humanbulk RNA-seq

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