Author

Christopher N. LaRock

Emory UniversityORCID 0000-0003-3035-5331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:bacteria (other)· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Doris L. LaRockiD· 2 shared Stephanie Guerra· 2 shared Ananya DashiD· 1 shared Claire QuiD· 1 shared Josh SuniD· 1 shared Keya Trivedi· 1 shared Mary A CarriD· 1 shared Sophia R ChouiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

Doris L. LaRockORCID

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Author profile →

4 papers

Recent·Most cited

Impact of cathelicidin cleavage by SpeB on Streptococcus pyogenes CovRS signaling

Stephanie Guerra, Claire Qu, Christopher N. LaRock

This study shows that SpeB cleavage of LL-37 does not impair CovRS signaling or reduce Spy's resistance to LL-37.

bioRxiv · Aug 12, 2026 · PreprintMicrobiology

A protease-sensing circuit links neutrophil inflammation to virulence regulation in Streptococcus pyogenes

Stephanie Guerra, Ananya Dash, Doris L. LaRock, Christopher N. LaRock

This study identifies a protease-sensing circuit in Streptococcus pyogenes linking neutrophil inflammation to virulence regulation through SpeB and Vfr interactions.

bioRxiv · May 15, 2026 · PreprintMicrobiology

Therapeutic Inhibition of Metalloproteases by Tetracyclines during Infection by Multi-Drug Resistant Pseudomonas

Mary A Carr, Sophia R Chou, Josh Sun, Doris L. LaRock, Christopher N. LaRock

This study shows tetracycline antibiotics inhibit Pseudomonas LasB protease, reduce inflammation, and enhance neutrophil killing of bacteria in pulmonary infections.

The Journal of Infectious Diseases · Jul 4, 2025Peer-reviewedMicrobiology

Pentamidine inhibition of streptopain attenuates Streptococcus pyogenes virulence

Keya Trivedi, Christopher N. LaRock

This study identifies pentamidine as an inhibitor of streptopain, reducing Streptococcus pyogenes virulence and enhancing susceptibility to immune cells.

Microbiology Spectrum · Jun 23, 2025Peer-reviewedMicrobiology