Author

Doris L. LaRock

Emory UniversityORCID 0000-0002-2661-6853Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Organism:mouse· 1

Frequent Co-Authors

Christopher N. LaRockiD· 2 shared Ananya DashiD· 1 shared Josh SuniD· 1 shared Mary A CarriD· 1 shared Sophia R ChouiD· 1 shared Stephanie Guerra· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

Christopher N. LaRockORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 15, 2026

A protease-sensing circuit links neutrophil inflammation to virulence regulation in Streptococcus pyogenes

Stephanie Guerra, Ananya Dash, Doris L. LaRock, Christopher N. LaRock

This study identifies a protease-sensing circuit in Streptococcus pyogenes linking neutrophil inflammation to virulence regulation through SpeB and Vfr interactions.

DOI 10.64898/2026.05.15.725401

bacteria (other)proteomics

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MicrobiologyThe Journal of Infectious DiseasesPeer-reviewedJul 4, 2025

Therapeutic Inhibition of Metalloproteases by Tetracyclines during Infection by Multi-Drug Resistant Pseudomonas

Mary A Carr, Sophia R Chou, Josh Sun…·Christopher N. LaRock

This study shows tetracycline antibiotics inhibit Pseudomonas LasB protease, reduce inflammation, and enhance neutrophil killing of bacteria in pulmonary infections.

3 citations

mouseproteomics

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