Synthetic BiologySciencePeer-reviewed
✦ In-depth digest
Sequence modeling and design from molecular to genome scale with Evo
Eric Nguyen, Michael Poli, Matthew G. Durrant…·Brian Hie
7B-parameter convolution-attention DNA model with 131 kb context, trained on prokaryotic genomes, performs zero-shot fitness and essentiality prediction and generates Cas loci, transposons, and 650 kb sequences.
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