NeuroscienceBehavioral and Brain FunctionsPeer-reviewed
FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment
Mengdie Li, Yating Yang, Tangcong Chen…·Michael H. J. Maes
This study shows that FTO deficiency worsens age-related depression-like behaviors and cognitive impairment in mice by impairing hippocampal synaptic plasticity.
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