Jiankang Wang

The paper introduces a cohesin-centric gene regulatory network database that integrates TF binding, regulatory sites, and gene targets to enhance GRN reconstruction.

The paper identifies a new subset of cohesin binding sites, DICs, with distinct functions in transcriptional regulation across human cell types.

This study investigates how cohesin and related factors regulate 3D genome structure and gene expression by analyzing depletion effects on chromatin, transcriptome, and epigenome data.