Jay Pavelka

SALVE predicts interorgan communication by analyzing RNA-seq data to link secretome-encoding transcripts with gene modules in distal organs, identifying new candidate organokines and their signaling mechanisms.

This study uses deuterium labeling to analyze protein turnover kinetics in hiPSCs and identifies fast-turnover proteins involved in cell division and differentiation.

This paper introduces a method to improve protein turnover rate calculation using heavy water labeling and mass spectrometry, increasing coverage of well-fitted peptides by 25-82% in mouse organ proteomes.