Author

Alexander Black

University of Colorado Anschutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Edward LauiD· 4 shared Maggie P. Y. LamiD· 4 shared Boomathi PandiiD· 3 shared Dominic C. M. NgiD· 3 shared Jay PavelkaiD· 2 shared Jordan CurrieiD· 2 shared Lorena AlamilloiD· 2 shared Timothy A. McKinseyiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersBiochemistry

Edward LauORCID

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Author profile →

4 papers

Recent·Most cited

Subcellular spatiotemporal proteomics delineates distinct phases of ER stress proteostatic response

Lorena Alamillo, Thalia Paiz, Alexander Black, Matthew C. Juber, Ethan M. Arends, Jacob G. Cox, Dominic C M Ng, Timothy A. McKinsey, Maggie P. Y. Lam, Edward Lau

This study uses SPLAT-TR to analyze proteome changes in ER stress, revealing distinct temporal phases of protein translocation, clearance, and degradation in different organelles.

bioRxiv · Sep 28, 2026 · PreprintBiochemistry

Micro- and macro- heterogeneity of N-glycoproteome remodeling in endoplasmic reticulum stress

Alexander Black, Tiffany Ngo, Boomathi Pandi, Andrew Mongin, Dominic C. M. Ng, Edward Lau, Maggie P. Y. Lam

The paper develops an mPBA enrichment workflow to analyze N-glycoproteome remodeling under ER stress, revealing dynamic changes in glycosylation sites and glycoforms.

Molecular & Cellular Proteomics · Sep 1, 2026Peer-reviewedBiochemistry

Deuterium labeling enables proteome wide turnover kinetics analysis in cell culture

Lorena Alamillo, Dominic C. M. Ng, Jordan Currie, Alexander Black, Boomathi Pandi, Vyshnavi Manda, Jay Pavelka, Peyton Schaal, Joshua G. Travers, Timothy A. McKinsey, Maggie P. Y. Lam, Edward Lau

This study uses deuterium labeling to analyze protein turnover kinetics in hiPSCs and identifies fast-turnover proteins involved in cell division and differentiation.

Cell Reports Methods · Jul 1, 2025Peer-reviewedBiochemistry

Improved determination of protein turnover rate with heavy water labeling by mass isotopomer ratio selection

Jordan Currie, Dominic C. M. Ng, Boomathi Pandi, Alexander Black, Vyshnavi Manda, Cheyanne Durham, Jay Pavelka, Maggie P. Y. Lam, Edward Lau

This paper introduces a method to improve protein turnover rate calculation using heavy water labeling and mass spectrometry, increasing coverage of well-fitted peptides by 25-82% in mouse organ proteomes.

Journal of Proteome Research · Mar 18, 2025Peer-reviewedBiochemistry