Activation of the mPFC-NAc pathway reduces motor impulsivity but does not affect risk-related decision-making in innately high-impulsive rats
Chloé Arrondeau, Ginna Urueña‐Méndez, Florian Marchessaux…·Nathalie Ginovart
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Chloé Arrondeau, Ginna Urueña‐Méndez, Florian Marchessaux…·Nathalie Ginovart
Ginna Urueña‐Méndez, Chloé Arrondeau, Florian Marchessaux…·Nathalie Ginovart
The paper investigates the role of the mPFC-to-VTA pathway in impulsive action and risk-related decision-making in rats, finding it modulates impulsive action but not decision-making.
Raphaël Goutaudier, Fanny Joly, David Mallet…·Sébastien Carnicella
David Mallet, Raphaël Goutaudier, Emmanuel Barbier…·Sabrina Boulet
This study shows that MSDC-0160, a mitochondrial pyruvate carrier inhibitor, reduces neurodegeneration in a rat Parkinson's disease model by altering energy metabolism and neuroinflammation.
Raphaël Goutaudier, Véronique Coizet, Carole Carcenac, Sébastien Carnicella
This study evaluates Compound 21's selectivity and off-target effects in modulating nigral dopaminergic neurons in rats, finding dose-dependent differences between males and females.