Sébastien Carnicella

The paper identifies miR-10a-5p as a molecular regulator of impulsivity in the nucleus accumbens, linking it to dopaminergic signaling and impulsive-compulsive disorders.

This study shows pramipexole reduces impulsivity in highly impulsive rats by modulating frontostriatal networks, specifically through Zif268 mRNA downregulation in the nucleus accumbens core.

This study shows that MSDC-0160, a mitochondrial pyruvate carrier inhibitor, reduces neurodegeneration in a rat Parkinson's disease model by altering energy metabolism and neuroinflammation.

This study evaluates Compound 21's selectivity and off-target effects in modulating nigral dopaminergic neurons in rats, finding dose-dependent differences between males and females.

This study compares the effects of unilateral and bilateral subthalamic nucleus deep brain stimulation on apathy, depression, and anxiety in Parkinson's disease using pre-clinical and clinical approaches.