Rolandas Meškys

The paper identifies ASCH domain-containing proteins as tRNA N4-acetylcytidine erasers, revealing their conserved deacetylase activity across species.

This study identifies RudS as a bacterial tRNA de-modifying enzyme that removes 4-thiouridine, with experimental and computational evidence supporting its catalytic function and tRNA binding mechanism.

This paper introduces ProteinGAN, a GAN that generates functional protein sequences, showing 24% of generated sequences are soluble and active in vitro.