Author

Masakazu Hashimoto

Fukushima Medical UniversityORCID 0000-0003-3184-9093Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Hiroshi SasakiiD· 3 shared Hinako MaedaiD· 1 shared Hiromi ShimojoiD· 1 shared Jiahang MiaoiD· 1 shared Kazuhiro OkumuraiD· 1 shared Masatoshi HaraiD· 1 shared Naoki HironoiD· 1 shared Tatsuo FukagawaiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Hiroshi SasakiORCID

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedDec 4, 2024

Fate specification triggers a positive feedback loop of TEAD-YAP and NANOG to promote epiblast formation in preimplantation embryos

Naoki Hirono, Masakazu Hashimoto, Hinako Maeda…·Hiroshi Sasaki

The paper shows that epiblast fate specification involves a positive feedback loop between NANOG and TEAD-YAP, which stabilizes the epiblast fate.

3 citations

mouseexperimental assay

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Cell BiologyLife Science AlliancePeer-reviewedOct 21, 2024

CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation

Weixia Kong, Masatoshi Hara, Yurika Tokunaga…·Tatsuo Fukagawa

The paper identifies a regulatory loop between CENP-C and Aurora B kinase mediated by the Mis12 complex, essential for correcting kinetochore-microtubule attachment errors during mitosis.

8 citations

humanexperimental assay

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Developmental BiologyDevelopmental CellPeer-reviewedJun 13, 2019

Epiblast formation by Tead-Yap-dependent expression of pluripotency factors and competitive elimination of unspecified cells

Masakazu Hashimoto, Hiroshi Sasaki

The paper identifies Tead-Yap regulation of pluripotency factors and cell competition in epiblast formation, showing Tead activity drives pluripotency and eliminates unspecified cells.

140 citationstop 1%

mousestatistical model

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