BiochemistryArchives of Biochemistry and BiophysicsPeer-reviewed
Structural, dynamic, and evolutionary determinants of substrate binding in the tetrameric 6-phosphogluconate dehydrogenase from Gluconobacter oxydans
Pablo Maturana, Pablo Villalobos, Pietro Roversi, Ricardo Cabrera
This study identifies a substrate-induced quaternary-tightening mechanism in tetrameric 6PGDH from Gluconobacter oxydans, revealing how conserved C-terminal elements regulate substrate binding and catalysis.
DOI 10.1016/j.abb.2026.110779