Mitra Esfandiarei

This study investigates the role of caveolin-1 in aortic root aneurysm development in MFS mice by examining its effects on endothelial and smooth muscle function, showing that Cav1 ablation increases NO production and improves aortic wall structure.

This study finds increased apoptosis in cortical neurons of female MFS mice compared to controls, with elevated BDNF levels in both sexes.

This study shows that maternal dietary deficiency in choline or folic acid reduces MMP-2 levels in blood and brain tissue of male offspring mice after ischemic stroke.

This study investigates cerebrovascular and neuroinflammatory changes in a Marfan Syndrome mouse model, finding premature aging characteristics in the brain similar to aged controls.

This study examines sex-dependent vascular dysfunction in FBN1 mutation mice, finding premature vascular aging and sex-specific changes in blood flow and structure.

This study examines how maternal deficiencies in folic acid or choline affect cerebral and peripheral blood flow in female mouse offspring after ischemic stroke.