Jean‐Pierre Saint‐Jeannet

Human stem cell model of neural crest cell differentiation reveals a requirement of SF3B4 in survival, maintenance, and differentiation

This study uses hESCs to model Nager and Rodriguez syndromes, showing SF3B4 is essential for neural crest cell survival, maintenance, and differentiation.

Sf3b4 mutation in Xenopus tropicalis causes RNA splicing defects followed by massive gene dysregulation that disrupt cranial neural crest development

This study shows that homozygous sf3b4 deletion in Xenopus tropicalis causes splicing defects and gene dysregulation, disrupting cranial neural crest development and leading to Nager syndrome-like features.

Paracrine regulation of neural crest EMT by placodal MMP28

The paper shows MMP28 from placodal cells promotes neural crest EMT and migration by entering the nucleus of neural crest cells in Xenopus.

Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

This study identifies Npr3's dual role in regulating neural crest and cranial placode progenitor formation through clearance and signaling functions in natriuretic peptide signaling.

Dynamic expression of MMP28 during cranial morphogenesis

The paper describes the expression pattern of MMP28 in Xenopus laevis embryos during cranial morphogenesis.