Author

Dror Brook

Weizmann Institute of ScienceORCID 0000-0003-3276-9941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Adrian DuekiD· 2 shared Gal DadiiD· 2 shared Hadas Naor· 2 shared Liran I. ShlushiD· 2 shared Nathali KaushanskyiD· 2 shared Nili Furer· 2 shared Oren MilmaniD· 2 shared Sigal Tavor· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Adrian DuekORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Circulating hematopoietic stem and progenitor cells in myeloproliferative neoplasms

Gal Dadi, Oren Milman, Nili Furer…·Liran I. Shlush

This study profiles circulating hematopoietic stem and progenitor cells in MPN patients, identifying transcriptional signatures and quantitative readouts to distinguish MF from other MPNs and predict progression.

DOI 10.64898/2026.10.26.761833

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintAug 26, 2025

Deciphering the Origin and Plasticity of Circulating Endothelial Cells: A Model for Systemic Angiogenesis Programs in Health and Disease

Orly Efros, Dror Brook, Yotam Yaniv…·Liran I. Shlush

This study identifies and characterizes circulating endothelial cells (CECs) using single-cell data, revealing their diverse origins and plasticity, and links them to angiogenic programs in cancer.

DOI 10.1101/2025.08.26.672338

humanscRNA-seq

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GenomicsbioRxivPreprintAug 16, 2022

A local sequence signature defines a subset of heterochromatin-associated CpGs with minimal loss of methylation in healthy tissues but extensive loss in cancer

Dror Bar, Lior Fishman, Yueyuan Zheng…·Benjamin P. Berman

The paper identifies a sequence signature that predicts CpG methylation loss in healthy tissues and cancer, revealing slow-loss CpGs with minimal methylation loss in health but significant loss in cancer.

4 citations

humanDNA methylation

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