Deciphering the Origin and Plasticity of Circulating Endothelial Cells: A Model for Systemic Angiogenesis Programs in Health and Disease
Orly Efros, Dror Brook, Yotam Yaniv, Jacob Elkahal, Nili Furer, Gal Dadi, Hadas Naor, Nimrod Rappoport, Oren Milman, Merav Kedmi, Uriel Katz, Sigal Tavor, Adrian Duek, Elad Maor, Leonid Sternik, , Liran I. Shlush
This study identifies and characterizes circulating endothelial cells (CECs) using single-cell data, revealing their diverse origins and plasticity, and links them to angiogenic programs in cancer.
bioRxiv · Aug 26, 2025 · PreprintMolecular Biology