Author

Sandra Sigala

University of BresciaORCID 0000-0003-3294-4121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Mariangela TamburelloiD· 3 shared Andrea AbateiD· 2 shared Aimee Di MarcoiD· 1 shared Alessia InglesiiD· 1 shared Alfredo BerrutiiD· 1 shared Barbara AltieriiD· 1 shared Carles Gaston‐MassuetiD· 1 shared Celso E. Gómez-SáncheziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Mariangela TamburelloORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 19, 2026

A multilayered in silico analysis links UHRF1, DNA methylation and developmental chromatin memory to lineage-dependent prognosis in gastric, renal and adrenal cancers

Jacopo Biotti, Livio Muccillo, Filippo Macchi…·Ian Marc Bonapace

The paper identifies a UHRF1-EM framework linking DNA methylation, developmental chromatin states, and prognosis in gastric, renal, and adrenal cancers, showing context-dependent prognostic associations.

DOI 10.64898/2026.08.14.742686

humanbulk RNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologyEndocrine Related CancerPeer-reviewedMay 1, 2026

Updating ACC preclinical models: characterization of two new patient-derived cell lines

Andrea Abate, Mariangela Tamburello, Claudia Bonera…·Sandra Sigala

This paper describes the development and characterization of two new patient-derived ACC cell lines, SMAC-2 and SMAC-3, highlighting their molecular and functional features for preclinical research.

DOI 10.1530/erc-25-0317

humanbulk RNA-seq

𝕏 PostBluesky

Cancer Biology癌症：英文版Peer-reviewedMar 4, 2025

Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma

Katia Mariniello, James F. H. Pittaway, Barbara Altieri…·Leonardo Guasti

This paper identifies DLK1 as a marker of adrenocortical stem/progenitor cells that predicts malignancy in adrenocortical carcinoma and is detectable in patient serum.

12 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky