Systems BiologyPLoS Computational BiologyPeer-reviewed
Modeling large fluctuations of thousands of clones during hematopoiesis: the role of stem cell self-renewal and bursty progenitor dynamics in rhesus macaque
Song Xu, Sanggu Kim, Irvin S. Y. Chen, Tom Chou
The paper models clone fluctuations in rhesus macaque hematopoiesis, showing that stochastic HSC self-renewal and progenitor proliferation constraints explain large temporal variations in clone abundance.
17 citations