Song Xu

Inhibition of hexokinase 2 undermines cartilage health and accelerates osteoarthritis

This study shows that inhibiting hexokinase 2 (HK2) impairs cartilage formation and accelerates osteoarthritis progression in mice.

Structural variation discovery in wheat using PacBio high-fidelity sequencing

This study evaluates SV detection methods using HiFi sequencing in wheat, finding optimal aligners and callers and demonstrating low-coverage HiFi sequencing is sufficient for accurate SV discovery.

Improvement in Outcomes and Prevention of Multiple Organ Dysfunction Syndrome After Cardiac Arrest and Successful Cardiopulmonary Resuscitation by Systemic Administration of Bumetanide in Male Mice

This study shows that systemic bumetanide administration after cardiac arrest and CPR improves survival, reduces brain injury, and prevents multiple organ dysfunction in male mice, with LCN2/NGAL identified as a potential biomarker for early neuroprognostication.

Population genomics unravels the Holocene history of Triticum-Aegilops species

This study uses whole-genome sequences of 795 wheats to trace the population history of bread wheat and its relatives, revealing origins, speciation, and spread across Eurasia.

Mapping Transcriptomic Vector Fields of Single Cells

The paper introduces dynamo, a framework for estimating RNA velocities and predicting cell fates using single-cell RNA-seq data, applied to various biological processes.