Author

James Oliver Lindsay

Barts Health NHS TrustORCID 0000-0003-3353-9590Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Andrew J. StaggiD· 2 shared Achuth H. ShenoyiD· 1 shared Ailsa L HartiD· 1 shared Aleksejs SazonovsiD· 1 shared Alistair McNair· 1 shared Alka Thakur· 1 shared Amanda Beale· 1 shared Amer AzaziD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Andrew J. StaggORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 17, 2025

Bacterial suppression of intestinal fungi via activation of human gut γδ T-cells

Liya Mathew, Sean Carlson, Michael Savage…·Neil E. McCarthy

The paper shows that bacterial metabolite HMB-PP activates human gut γδ T-cells to suppress fungal growth, but this mechanism is impaired in Crohn's disease.

DOI 10.1101/2025.09.17.676560

humanproteomics

𝕏 PostBluesky

GenomicsJournal of Cellular and Molecular MedicinePeer-reviewedApr 29, 2024

Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohns disease

David T. Humphreys, Amy Lewis, Belen Pan‐Castillo…·Andrew R. Silver

The paper uses single-cell RNA sequencing to identify distinct B cell and fibroblast populations in stricturing Crohn's disease, highlighting their potential roles in fibrosis.

21 citationstop 3%

humanscRNA-seq

𝕏 PostBluesky

GenomicsGastroenterologyPeer-reviewedOct 7, 2019

HLA-DQA1*05 is associated with the development of antibodies to anti-TNF therapy

Aleksejs Sazonovs, Nicholas Alexander Kennedy, Loukas Moutsianas…·Thankam Paul

This study identifies HLA-DQA1*05 as a genetic risk factor for anti-drug antibody development in Crohn's disease patients treated with anti-TNF therapies.

424 citationstop 1%

humanstatistical model

𝕏 PostBluesky