Author

Chizoba N. Umeweni

Children's Hospital of PhiladelphiaORCID 0000-0003-3359-9593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda B. MuiriD· 2 shared Benjamin J. WilkinsiD· 2 shared Diya DhakaliD· 2 shared Emily A. McMillan· 2 shared Hailey Golden· 2 shared Heidi WintersiD· 2 shared Kanak V. Kennedy· 2 shared Kelly A. WhelaniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Amanda B. MuirORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJan 29, 2026

Prostaglandin E2 Reverses Myofibroblast Differentiation in Eosinophilic Esophagitis

Ryugo Teranishi, Takefumi Itami, Masaru Sasaki…·Amanda B. Muir

This study shows that Prostaglandin E2 reverses myofibroblast differentiation in EoE via the cAMP/YAP/THBS-1 pathway, suggesting it as a potential treatment for fibrostenotic EoE.

1 citation

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintMay 25, 2025

FOXM1 Modulation Alleviates Epithelial Remodeling and Inflammation in Eosinophilic Esophagitis

Masaru Sasaki, Joshua X. Wang, Yusen Zhou…·Amanda B. Muir

This study identifies FOXM1 as a key driver of epithelial disruption in EoE, showing that its inhibition restores differentiation, reduces hyperplasia, and improves barrier function.

1 citation

humanmouse

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