Philippe Lopez

GenDiMug is a multigraph framework for analyzing genomic organization and multi-omics data across scales, revealing gene expression clumping and circadian regulation in a photosynthetic alga.

The paper investigates how cardiolipin (CL) affects H+ concentration and movement at mitochondrial membranes, finding that CL increases surface H+ activity and enables reversible acidification fronts.

This study analyzes the cell cycle of Saccharolobus islandicus and finds that transcriptional patterns are conserved with eukaryotes, showing phase-specific gene expression for metabolism, protein synthesis, and chromatinization.

The paper identifies new divergent protein groups in ancient gene families from marine metagenomes, highlighting environmental diversity and potential biological novelty.

This study analyzes 60 brown algal genomes to identify genomic innovations and evolutionary patterns that enabled their adaptation to coastal ecosystems.

RRNPP_detector identifies RRNPP quorum sensing systems in gram-positive bacteria genomes, revealing expanded diversity and novel regulatory mechanisms.

The paper identifies viral quorum sensing systems that manipulate bacterial sporulation timing through density-dependent mechanisms, revealing convergent evolution in bacteriophages.