Yanyan Li

The paper identifies a family of over 2000 lanthipeptide biosynthetic gene clusters in Actinobacteria with anti-phage function, demonstrating their conservation and novel compound production.

The paper identifies a new family of dehydrating condensation domain proteins involved in the biosynthesis of azabicyclocarbamates in Pseudomonas aeruginosa.

The paper identifies 5-thiooxazoles as the cysteine post-translational modifications in bufferins using isotopic labeling and confirms consistency with related MNIO families.

This study shows that lasso peptides sviceucin and siamycin I reduce virulence and restore vancomycin effectiveness against resistant bacteria by targeting histidine kinases.

The paper identifies and characterizes the diversity of substrates and partner proteins for multinuclear non-heme iron-dependent oxidative (MNIO) enzymes, revealing new insights into their role in bacterial copper homeostasis and potential broader stress responses.

This paper identifies bufferins, a widespread family of ribosomal peptide metallophores that help bacteria adapt to copper stress by sequestering excess copper ions.

RRNPP_detector identifies RRNPP quorum sensing systems in gram-positive bacteria genomes, revealing expanded diversity and novel regulatory mechanisms.

The paper identifies viral quorum sensing systems that manipulate bacterial sporulation timing through density-dependent mechanisms, revealing convergent evolution in bacteriophages.