BiochemistryThe Journal of Physical Chemistry BPeer-reviewed
Preventing pathogenic dimerization in a misfolded antibody light chain through the design of an inhibitory peptide
Fausta Desantis, Mattia Miotto, Edoardo Milanetti…·Lorenzo Di Rienzo
This study designs an inhibitory peptide to prevent pathogenic dimerization of a misfolded antibody light chain by optimizing its sequence to maximize interface complementarity.
DOI 10.1021/acs.jpcb.5c07238