Max Adriaan Verbiest

ConSTRain is a novel STR variant caller that accounts for copy number alterations, enabling accurate genotyping in polyploid and aneuploid organisms.

The paper identifies STR variations associated with gene expression and DNA methylation across three cancer types and finds shared regulatory mechanisms.

The paper identifies a novel hyper-VNTR in SLC6A3, characterized by high heterozygosity, G-quadruplex formation, and potential recombination hotspot properties.