Abner T. Apsley

The paper develops spatially-resolved models of the yeast galactose switch to show how intracellular organization affects regulatory dynamics.

The paper characterizes RNA and protein expression in synthetic bacteria Syn1.0 and Syn3A, showing genome minimization alters gene expression and resource allocation.

The paper compares epigenetic aging clocks across different tissue types, finding significant differences in age estimates between oral and blood-based tissues.

The paper compares telomere length and DNA quality metrics across five tissues in individuals aged 8 to 70 years, finding age-related shortening in most tissues and tissue-specific variations in DNA quality.

The paper identifies a novel hyper-VNTR in SLC6A3, characterized by high heterozygosity, G-quadruplex formation, and potential recombination hotspot properties.

This study analyzes DNA methylation changes in humans undergoing calorie restriction, finding CR-induced DNAm changes opposite BMI and smoking associations and aligned with aging-related CpG sites.