Author

Yan Chen

Fudan UniversityORCID 0000-0003-3457-2560Unclaimed ORCID profile · follow to get notified of new preprints

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Yan Chen15 papers · Chinese Academy of Sciences

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:diffusion model· 1 Research Focus:imputation· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Boyu LyuiD· 1 shared Congcong Xia· 1 shared Fang LuoiD· 1 shared Feifei CuiiD· 1 shared Guoming MaiD· 1 shared Guoqiang YuiD· 1 shared Hua Wang ShiiD· 1 shared Jie LiuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Boyu LyuORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 12, 2025

DiffusionST: A deep generative diffusion model-based framework for enhancing spatial transcriptomics data quality and identifying spatial domains

Yaxuan Cui, Yang Cui, Ruheng Wang…·Leyi Wei

DiffusionST improves spatial transcriptomics data quality and identifies spatial domains through a diffusion model and graph convolutional network.

3 citations

humanspatial transcriptomics

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NeurosciencebioRxivPreprintOct 15, 2024

Integrated temporal profiling of iPSCs-derived motor neurons from ALS patients carrying C9orf72, FUS, TARDBP, and SOD1 mutations

Guoming Ma, Congcong Xia, Boyu Lyu…·Wenyuan Wang

This study profiles temporal RNA-seq in iPSC-derived motor neurons from ALS patients with specific mutations, identifying shared gene expression and splicing defects across different mutations.

1 citation

humanbulk RNA-seq

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