Author

Joe C. Udeochu

Gladstone InstitutesORCID 0000-0003-3463-2148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Lay KodamaiD· 2 shared Li GaniD· 2 shared Alvan CaiiD· 1 shared Andrew SingletoniD· 1 shared Anna Jovicic· 1 shared Bin ZhangiD· 1 shared Cesar Sanchez-DiaziD· 1 shared Cindy Tzu-Ling HuangiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Lay KodamaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 16, 2021

A CRISPRi/a platform in iPSC-derived microglia uncovers regulators of disease states

Nina M. Dräger, Sydney M. Sattler, Cindy Tzu-Ling Huang…·Martin Kampmann

This study uses a CRISPRi/a platform in iPSC-derived microglia to identify genes regulating microglia states and their therapeutic targets.

16 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 24, 2020

AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans

Faten A. Sayed, Lay Kodama, Joe C. Udeochu…·Li Gan

This study identifies R47H-TREM2 mutation-induced proinflammatory microglial states in human AD and tauopathy mice, showing Akt pathway involvement and potential therapeutic targets.

3 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 21, 2018

EXOSOME RELEASE PROMOTES INFLAMMATORY RESOLUTION IN ACTIVATED AND AGED MICROGLIA

Joe C. Udeochu, Cesar Sanchez-Diaz, Alvan Cai…·Saul Villeda

This study shows that exosome release promotes immune homeostasis in activated and aged microglia by modulating inflammatory pathways and cargo trafficking.

8 citations

mouseexperimental assay

𝕏 PostBluesky