GenomicsbioRxivPreprint
CRAG: De novo characterization of cell-free DNA fragmentation hotspots in plasma whole-genome sequencing
Xionghui Zhou, Haizi Zheng, Hailu Fu…·Yaping Liu
The paper develops a method to identify cell-free DNA fragmentation hotspots in plasma whole-genome sequencing and shows their utility in detecting early-stage cancers with high specificity and sensitivity.
3 citations