Author

David C. Samuels

Vanderbilt UniversityORCID 0000-0003-3529-7791Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

James T. Baker· 2 shared Jennifer Elizabeth BelowiD· 2 shared Alexandra ScaliciiD· 1 shared Anastasia A. Astafyev· 1 shared Chad Daniel HuffiD· 1 shared Dan M. RodeniD· 1 shared Danny G. WinderiD· 1 shared Dharmendra Choudhary· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

James T. Baker

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintNov 25, 2025

Common variant approaches to study Mendelian disease gene function identify novel phenome and pathways associated with PLOD3

Alexandra Scalici, James T. Baker, Freida Blostein…·Nancy Jean Cox

DOI 10.1101/2025.11.25.25340832

humanelectronic health records

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintApr 19, 2023

Detection of distant familial relatedness in biobanks for identification of undiagnosed carriers of a Mendelian disease variant: application to Long QT Syndrome

Megan Cummins Lancaster, Hung‐Hsin Chen, Moore Benjamin Shoemaker…·Jennifer Elizabeth Below

This paper develops a method to identify undiagnosed carriers of a rare Mendelian disease variant by detecting distant familial relatedness in biobanks.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 16, 2021

Targeting Diacylglycerol Lipase to Reduce AlcoholConsumption

Gaurav Bedse, Nathan D. Winters, Anastasia A. Astafyev…·Sachin Patel

This study shows that inhibiting diacylglycerol lipase reduces alcohol consumption in preclinical models and prevents ethanol-induced suppression of GABAergic transmission without causing anxiety or depression.

DOI 10.1101/2021.02.16.431429

mouseexperimental assay

𝕏 PostBluesky