From resting state to inactivation: the dynamic journey of the inactivation peptide in Shaker Kv channels
Roshan Pandey, Tanja Kalstrup, Rikard Blunck
The paper tracks the movement of the inactivation peptide in Shaker Kv channels during N-type inactivation using voltage clamp fluorometry and FRET techniques, revealing a biphasic mechanism involving release and pore blockage.
bioRxiv · Jul 10, 2024 · PreprintBiophysics