Author

Ekaterina Petrenko

Technion – Israel Institute of TechnologyORCID 0000-0003-3549-834XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Dvir AraniD· 2 shared Alma Sophia Barisaac· 1 shared Chen Yanovich-Ben-Uriel· 1 shared Enas R. Abu‐Zhayia· 1 shared Nabieh AyoubiD· 1 shared Or HevdeliiD· 1 shared Ziv CoheniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBioinformatics

Dvir AranORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedDec 11, 2025

CellMentor: Cell-Type Aware Dimensionality Reduction for Single-cell RNA-Sequencing Data

Or Hevdeli, Ekaterina Petrenko, Dvir Aran

CellMentor improves dimensionality reduction for scRNA-seq by preserving cell-type-specific signals and reducing batch effects across datasets.

DOI 10.1038/s41467-025-67088-7

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BioinformaticsNAR Genomics and BioinformaticsPeer-reviewedMar 29, 2025

SLAYER: A Computational Framework for Identifying Synthetic Lethal Interactions through Integrated Analysis of Cancer Dependencies

Ziv Cohen, Ekaterina Petrenko, Alma Sophia Barisaac…·Dvir Aran

SLAYER identifies synthetic lethal interactions by integrating cancer genomic data and CRISPR screens, finding 142 high-confidence candidates with 15-fold enrichment over random pairs.

3 citations

humanCRISPR screen

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