Ziv Cohen

SLAYER identifies synthetic lethal interactions by integrating cancer genomic data and CRISPR screens, finding 142 high-confidence candidates with 15-fold enrichment over random pairs.

This study shows how a Western-style diet alters gut microbiota and sulfur metabolism in mice, linking these changes to increased cancer risk and similar patterns in human colorectal cancer patients.

The paper develops a machine learning model to identify functional lncRNAs and validates SNHG6's role in hematopoietic differentiation and leukemia.