GenomicsThe EMBO JournalPeer-reviewed
Single cell regulatory architecture of human pancreatic islets suggests sex differences in β cell function and the pathogenesis of type 2 diabetes.
Mirza Muhammad Fahd Qadir, Ruth M. Elgamal, Kejing Song…·Franck Mauvais‐Jarvis
The paper examines sex and race differences in human pancreatic islets using scRNA-seq and snATAC-seq, finding sex-specific gene expression and chromatin accessibility differences in β cells that change with type 2 diabetes.