Author

Merel Rijnsburger

Amsterdam NeuroscienceORCID 0000-0003-3571-5439Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andy ChevignéiD· 1 shared Desislava N. NeshevaiD· 1 shared Henry F. VischeriD· 1 shared Iwan J. P. de EschiD· 1 shared Justyna M. AdamskaiD· 1 shared Maikel WijtmansiD· 1 shared Martyna SzpakowskaiD· 1 shared Maurice C. M. L. BuzinkiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Andy ChevignéORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyMolecular PharmacologyPeer-reviewedOct 26, 2025

Inhibition of constitutive activity of the atypical chemokine receptor ACKR3 by the small-molecule inverse agonist VUF16840

Reggie Bosma, Desislava N. Nesheva, Merel Rijnsburger…·Rob Leurs

This study characterizes VUF16840 as a selective inverse agonist of ACKR3 that inhibits constitutive and chemokine-induced signaling by stabilizing the inactive conformation of the receptor.

5 citations

humanexperimental assay

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