NeurosciencebioRxivPreprint
SNCA-targeted epigenome therapy for Parkinsons disease alleviates pathological and behavioral perturbations in a mouse model
Bernadette O’Donovan, Joseph E. Rittiner, Suraj Upadhya…·Ornit Chiba‐Falek
This study demonstrates that SNCA-targeted epigenome therapy reduces α-synuclein expression, aggregation, and motor deficits in a PD mouse model.
DOI 10.1101/2025.06.16.659948