Author

Tima Shamekhi

Hudson Institute of Medical ResearchORCID 0000-0003-3597-4086Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Pouya FaridiiD· 3 shared Claire Xin SuniD· 2 shared Isaac B. WoodhouseiD· 2 shared Nivedhitha SelvakumariD· 2 shared Ralf B. SchittenhelmiD· 2 shared Ron FiresteiniD· 2 shared Terry C.C. Lim Kam SianiD· 2 shared Bettina KritzeriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCancer Biology

Pouya FaridiORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 30, 2026

Beyond HCD: complementary fragmentation chemistries expand HLA class I immunopeptidome discovery

Terry C.C. Lim Kam Sian, Fernanda Salvato, Nivedhitha Selvakumar…·Pouya Faridi

This paper evaluates CID and IRMPD fragmentation methods for HLA class I immunopeptidomics, finding they identify unique peptides missed by HCD, especially for non-basic anchor alleles and peptides lacking lysine, arginine, or histidine.

DOI 10.64898/2026.09.24.754253

humanproteomics

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Cancer BiologyiSciencePeer-reviewedOct 29, 2025

Resource: A Compendium of HLA-Type and Expression in Pediatric Cancer Models

Yu Guan, Ishika Mahajan, Vikesh Ajith…·Claire Xin Sun

The paper compiles HLA typing and expression data for 287 pediatric cancer cell lines to support immunotherapy research and personalized treatment development.

DOI 10.1016/j.isci.2025.113887

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintApr 7, 2025

H3K27M Mutation Reshapes the Antigenic Landscape in Diffuse Midline Glioma

Tima Shamekhi, Bijun Zeng, Claire Xin Sun…·Pouya Faridi

This study identifies six immunogenic peptides in diffuse midline glioma (DMG) linked to the H3K27M mutation, offering potential targets for T cell-based immunotherapy.

2 citations

humanproteomics

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