BioengineeringbioRxivPreprint
Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells
Dawn T. Bravo, Sriram Vaidyanathan, Jeanette B Baker…·Jayakar V. Nayak
This study demonstrates that gene-corrected human airway stem cells can durably engraft and restore CFTR function in murine respiratory epithelium, offering a potential therapy for cystic fibrosis.