Nicolas N. Madigan

This study develops a hydrogel scaffold with surface chemistry that promotes axon outgrowth and hindlimb recovery in spinal cord injury models.

This paper develops a novel scaffold biomaterial coated with extracellular matrix proteins to promote axonal regeneration after spinal cord injury.

This study quantifies spatial relationships between axons and blood vessels in hydrogel scaffolds after spinal cord injury using image analysis and stereologic methods.

This study shows that a cell-containing biomaterial scaffold promotes axon regeneration and spinal circuit reorganization, enhancing motor function recovery when combined with epidural electrical stimulation after spinal transection.

This study shows that a combinatorial biomaterials strategy with rapamycin and Schwann cells improves functional recovery and reduces fibrosis in rat spinal cord injury.

This study shows glucocorticoids inhibit spinal cord regeneration by directly affecting ependymal glia, contrasting with zebrafish regeneration mechanisms.