Riazul Islam

Segment-specific orientation of the dorsal and ventral roots for precise therapeutic targeting of human spinal cord

This study provides the first detailed analysis of segment-specific dorsal and ventral spinal roots orientation in humans, correlated with spinal cord and vertebral landmarks.

Newly regenerated axons through a cell-containing biomaterial scaffold promote reorganization of spinal circuitry and restoration of motor functions with epidural electrical stimulation.

This study shows that a cell-containing biomaterial scaffold promotes axon regeneration and spinal circuit reorganization, enhancing motor function recovery when combined with epidural electrical stimulation after spinal transection.

Changes in spinal cord hemodynamic reflect modulation of spinal network with different parameters of epidural stimulation

This study uses functional ultrasound imaging to show that spinal cord hemodynamic responses to epidural stimulation reflect changes in spinal circuitry organization based on stimulation parameters.

Multifactorial motor behavior assessment for real-time evaluation of emerging therapeutics to treat neurologic impairments

This paper introduces a novel method to assess motor behavior in rodents by integrating electrophysiological, biomechanical, and behavioral metrics during therapeutic interventions.