Kathleen R. Ryan

This paper reports the creation of macroscopic engineered living materials (ELMs) from Caulobacter crescentus cells using a de novo self-interacting protein matrix that can be genetically tuned for mechanical and functional properties.

This paper engineers a two-strain bacterial system to autonomously secrete and assemble a synthetic extracellular protein matrix, demonstrating programmable and high-yield biopolymer secretion.